Chelsea, under the guidance of Enzo Maresca, will take on Danish powerhouse FC Copenhagen in an eagerly anticipated clash.
Spanish side Real Betis is set to face Portugal’s Vitória Guimarães as they fight for a spot in the quarter-finals.
Meanwhile, last season’s finalists Fiorentina will navigate a challenging tie against Greek club Panathinaikos.
Elsewhere, Jagiellonia will clash with Cercle Brugge, Celje will face Lugano, and Molde will battle Legia Warsaw.
Swedish side Djurgården will take on Pafos, while Borac faces Austrian club SK Rapid in the final Round of 16 matchup.
As some of Europe’s top teams compete for the trophy, the tournament is set to heat up with high-stakes battles ahead.
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